CKMT1B anticorps

N° du produit ABIN6569428

Détail du produit anti-CKMT1B anticorps

Antigène: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKMT1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CKMT1B (NP_066270.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CKMT1B

Antigène: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Autre désignation: CKMT1B (CKMT1B Produits)

Synonymes: anticorps CKMT, anticorps CKMT1, anticorps UMTCK, anticorps ckmt, anticorps ckmt1, anticorps umtck, anticorps CKMT1A, anticorps creatine kinase, mitochondrial 1B, anticorps creatine kinase, mitochondrial 1B S homeolog, anticorps creatine kinase, mitochondrial 1B L homeolog, anticorps CKMT1B, anticorps ckmt1b.S, anticorps ckmt1b.L, anticorps ckmt1b

Sujet: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

Poids moléculaire:

Observed_MW: 47kDa

Calculated_MW: 47kDa/50kDa

ID gène: 1159

UniProt: P12532