PSMF1 anticorps

N° du produit ABIN6569980

Détail du produit anti-PSMF1 anticorps

Antigène: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMF1 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PSMF1 (NP_006805.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PSMF1

Antigène: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Autre désignation: PSMF1 (PSMF1 Produits)

Synonymes: anticorps PI31, anticorps AW048666, anticorps BC012260, anticorps zgc:92785, anticorps proteasome inhibitor subunit 1, anticorps proteasome (prosome, macropain) inhibitor subunit 1, anticorps PSMF1, anticorps Psmf1, anticorps psmf1

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.

Poids moléculaire:

Observed_MW: 30kDa

Calculated_MW: 29kDa

ID gène: 9491

UniProt: Q92530

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA