RBPJ anticorps

N° du produit ABIN6570040

Détail du produit anti-RBPJ anticorps

Antigène: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBPJ est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human RBPJ (NP_976028.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:20-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RBPJ

Antigène: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Autre désignation: RBPJ (RBPJ Produits)

Synonymes: anticorps AOS3, anticorps CBF1, anticorps IGKJRB, anticorps IGKJRB1, anticorps KBF2, anticorps RBP-J, anticorps RBPJK, anticorps RBPSUH, anticorps SUH, anticorps csl, anticorps AI843960, anticorps Igkjrb, anticorps Igkrsbp, anticorps RBP-J kappa, anticorps RBPjk, anticorps Rbpsuh, anticorps Su(H), anticorps XSu(H), anticorps xsu(h)1, anticorps Su(H)1, anticorps Su(h)A, anticorps ik:tdsubc_1e8, anticorps rbpj, anticorps rbpsuh, anticorps xx:tdsubc_1e8, anticorps Su(H)2, anticorps su(h)B, anticorps recombination signal binding protein for immunoglobulin kappa J region, anticorps recombination signal binding protein for immunoglobulin kappa J region S homeolog, anticorps recombination signal binding protein for immunoglobulin kappa J region a, anticorps recombination signal binding protein for immunoglobulin kappa J region b, anticorps RBPJ, anticorps Rbpj, anticorps rbpj.S, anticorps rbpja, anticorps rbpjb

Sujet: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.

Poids moléculaire:

Observed_MW: 55kDa

Calculated_MW: 45kDa/47kDa/51kDa/54kDa/55kDa

ID gène: 3516

UniProt: Q06330

Pathways: Signalisation Notch, Stem Cell Maintenance, Smooth Muscle Cell Migration