PEX5 anticorps

N° du produit ABIN6570114

Détail du produit anti-PEX5 anticorps

Antigène: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEX5 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PEX5 (NP_000310.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PEX5

Antigène: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Autre désignation: PEX5 (PEX5 Produits)

Synonymes: anticorps AW212715, anticorps ESTM1, anticorps PTS1R, anticorps Pxr1, anticorps X83306, anticorps PTS1-BP, anticorps PBD2A, anticorps PBD2B, anticorps PXR1, anticorps Peroxin-5, anticorps peroxisomal biogenesis factor 5, anticorps pex5, anticorps Pex5, anticorps PEX5

Sujet: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire:

Observed_MW: 70kDa

Calculated_MW: 66kDa/69kDa/70kDa/72kDa

ID gène: 5830

UniProt: P50542

Pathways: Monocarboxylic Acid Catabolic Process