C8orf4 anticorps
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- Antigène Voir toutes C8orf4 Anticorps
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp C8orf4 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human C8orf4 (NP_064515.1).
- Isotype
- IgG
- Top Product
- Discover our top product C8orf4 Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
- Autre désignation
- C8orf4 (C8orf4 Produits)
- Synonymes
- anticorps TC-1, anticorps TC1, anticorps 1110065B09Rik, anticorps AW121743, anticorps AW321058, anticorps C8ORF4, anticorps transcriptional and immune response regulator, anticorps chromosome 22 open reading frame, human C8orf4, anticorps TCIM, anticorps C22H8ORF4, anticorps Tcim
- Sujet
- This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
- Poids moléculaire
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Observed_MW: Refer to figures
Calculated_MW: 12kDa
- ID gène
- 56892
- UniProt
- Q9NR00
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