Adenylosuccinate Lyase anticorps

N° du produit ABIN6570325

Détail du produit anti-Adenylosuccinate Lyase anticorps

Antigène: Adenylosuccinate Lyase (ADSL)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenylosuccinate Lyase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human ADSL (NP_000017.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:20-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Adenylosuccinate Lyase

Antigène: Adenylosuccinate Lyase (ADSL)

Autre désignation: ADSL (ADSL Produits)

Synonymes: anticorps fi60b04, anticorps zgc:56061, anticorps wu:fi60b04, anticorps MGC53383, anticorps MGC69239, anticorps adsL, anticorps F15C21.8, anticorps F15C21_8, anticorps AMPS, anticorps ASASE, anticorps ASL, anticorps Adl, anticorps Asl, anticorps purB, anticorps adenylosuccinate lyase, anticorps adenylosuccinate lyase L homeolog, anticorps adenylosuccinase; ASL, anticorps Adenylosuccinate lyase, anticorps L-Aspartase-like family protein, anticorps ADSL, anticorps adsl, anticorps adsl.L, anticorps ASL, anticorps purB, anticorps purB,adsL, anticorps Mrub_2293, anticorps MMAH_RS02975, anticorps Arnit_0089, anticorps Mesil_1058, anticorps Slip_0597, anticorps Trad_2452, anticorps Deba_0652, anticorps Toce_1174, anticorps Acear_2324, anticorps Igag_0272, anticorps Saut_2156, anticorps Fbal_1996, anticorps Ndas_2434, anticorps Ilyop_0196, anticorps Lbys_2961, anticorps MFER_RS02920, anticorps Palpr_2192, anticorps Calni_0061, anticorps Ftrac_3746, anticorps AT1G36280, anticorps Olsu_1764, anticorps Adsl

Sujet: The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire:

Observed_MW: 47kDa

Calculated_MW: 48kDa/54kDa

ID gène: 158

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process