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HYOU1 anticorps

HYOU1 Reactivité: Humain, Souris IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6570576
  • Antigène Voir toutes HYOU1 Anticorps
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    Reactivité
    • 73
    • 27
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 44
    • 30
    Lapin
    Clonalité
    • 39
    • 36
    Polyclonal
    Conjugué
    • 28
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HYOU1 est non-conjugé
    Application
    • 65
    • 27
    • 24
    • 14
    • 14
    • 13
    • 13
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human HYOU1 (NP_001124463.1).
    Isotype
    IgG
    Top Product
    Discover our top product HYOU1 Anticorps primaire
  • Indications d'application
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    Autre désignation
    HYOU1 (HYOU1 Produits)
    Synonymes
    anticorps GRP-170, anticorps Grp170, anticorps HSP12A, anticorps ORP-150, anticorps ORP150, anticorps AI415631, anticorps CBP-140, anticorps Cab140, anticorps Orp150, anticorps id:ibd5056, anticorps wu:fd14c05, anticorps zgc:56019, anticorps HYOU1, anticorps orp150, anticorps GRP170, anticorps hypoxia up-regulated 1, anticorps hypoxia up-regulated protein 1, anticorps hypoxia up-regulated 1 S homeolog, anticorps HYOU1, anticorps Hyou1, anticorps hyou1, anticorps LOC100380749, anticorps hyou1.S
    Sujet
    The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants.
    Poids moléculaire

    Observed_MW: 150kDa

    Calculated_MW: 62kDa/111kDa

    ID gène
    10525
    UniProt
    Q9Y4L1
    Pathways
    ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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