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SAFB anticorps

SAFB Reactivité: Humain, Souris, Rat WB, IF, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6571462
  • Antigène Voir toutes SAFB Anticorps
    SAFB (Scaffold Attachment Factor B (SAFB))
    Reactivité
    • 40
    • 22
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 45
    • 10
    Lapin
    Clonalité
    • 44
    • 11
    Polyclonal
    Conjugué
    • 31
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SAFB est non-conjugé
    Application
    • 38
    • 21
    • 14
    • 14
    • 13
    • 12
    • 9
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human SAFB (NP_001188267.1).
    Isotype
    IgG
    Top Product
    Discover our top product SAFB Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    SAFB (Scaffold Attachment Factor B (SAFB))
    Autre désignation
    SAFB (SAFB Produits)
    Synonymes
    anticorps HAP, anticorps HET, anticorps SAF-B1, anticorps SAFB1, anticorps 3110021E02Rik, anticorps 5330423C17Rik, anticorps AU018122, anticorps D18386, anticorps E130307D12, anticorps zgc:55387, anticorps wu:fb40a03, anticorps wu:fd42g06, anticorps SAFB2, anticorps SAFB, anticorps scaffold attachment factor B, anticorps scaffold attachment factor B S homeolog, anticorps SAFB-like transcription modulator, anticorps Scaffold attachment factor B, anticorps SAFB, anticorps Safb, anticorps safb, anticorps safb.S, anticorps LOC5570070, anticorps CpipJ_CPIJ017179, anticorps Bm1_49330, anticorps LOAG_00080
    Sujet
    This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire

    Observed_MW: 150kDa

    Calculated_MW: 95kDa/102kDa

    ID gène
    6294
    UniProt
    Q15424
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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