IRS2 anticorps

N° du produit ABIN6571475

Détail du produit anti-IRS2 anticorps

Antigène: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRS2 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human IRS2 (NP_003740.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IRS2

Antigène: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Autre désignation: IRS2 (IRS2 Produits)

Synonymes: anticorps IRS2, anticorps si:dkeyp-24d6.1, anticorps IRS-2, anticorps 4PS, anticorps Irs-2, anticorps insulin receptor substrate 2, anticorps insulin receptor substrate 2a, anticorps insulin receptor substrate 2b, anticorps IRS2, anticorps irs2a, anticorps irs2b, anticorps Irs2

Sujet: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Poids moléculaire:

Observed_MW: 170kDa

Calculated_MW: 137kDa

ID gène: 8660

UniProt: Q9Y4H2

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process