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NOTCH4 anticorps

NOTCH4 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6571661
  • Antigène Voir toutes NOTCH4 Anticorps
    NOTCH4 (Notch 4 (NOTCH4))
    Reactivité
    • 44
    • 31
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 55
    • 3
    • 3
    • 2
    • 2
    Lapin
    Clonalité
    • 49
    • 16
    Polyclonal
    Conjugué
    • 33
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NOTCH4 est non-conjugé
    Application
    • 29
    • 17
    • 13
    • 13
    • 8
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein of human NOTCH4 (NP_004548.3).
    Isotype
    IgG
    Top Product
    Discover our top product NOTCH4 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    NOTCH4 (Notch 4 (NOTCH4))
    Autre désignation
    NOTCH4 (NOTCH4 Produits)
    Synonymes
    anticorps INT3, anticorps NOTCH3, anticorps Int-3, anticorps Int3, anticorps N4, anticorps Notch4, anticorps notch 4, anticorps neurogenic locus notch homolog protein 4, anticorps NOTCH4, anticorps Notch4, anticorps LOC100712850
    Sujet
    This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
    Poids moléculaire

    Observed_MW: 210kDa

    Calculated_MW: 39kDa/61kDa/209kDa

    ID gène
    4855
    UniProt
    Q99466
    Pathways
    Signalisation Notch
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