UGT1A1 anticorps (N-Term)

N° du produit ABIN657870

Détail du produit anti-UGT1A1 anticorps

Antigène: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Épitope: AA 65-90, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UGT1A1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This UGT1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-90 amino acids from the N-terminal region of human UGT1A1.

Clone: RB22607

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: UGT1A1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur UGT1A1

Antigène: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Autre désignation: UGT1A1 (UGT1A1 Produits)

Synonymes: anticorps BILIQTL1, anticorps GNT1, anticorps HUG-BR1, anticorps UDPGT, anticorps UDPGT 1-1, anticorps UGT1, anticorps UGT1A, anticorps Gnt1, anticorps UGT1A01, anticorps Udpgt-1a, anticorps UgtBr1, anticorps Udpgt, anticorps Ugt1, anticorps zgc:123097, anticorps UDP glucuronosyltransferase family 1 member A1, anticorps UDP glucuronosyltransferase 1 family, polypeptide A1, anticorps UDP-glucuronosyltransferase 1-1, anticorps UDP-glucuronosyltransferase, anticorps UDP-glucuronosyltransferase 1-6, anticorps UDP glucuronosyltransferase 1 family polypeptide a1, anticorps UGT1A1, anticorps Ugt1a1, anticorps LOC100065342, anticorps LOC100125517, anticorps LOC100229734, anticorps LOC100405984, anticorps LOC100511479, anticorps ugt1a1

Sujet: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome.

Poids moléculaire: 59591

ID gène: 54658

NCBI Accession: NP_000454

UniProt: P22309

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha