PCSK7 anticorps (C-Term)

N° du produit ABIN657966

Détail du produit anti-PCSK7 anticorps

Antigène: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Épitope: AA 692-721, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCSK7 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PCSK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human PCSK7.

Clone: RB34092

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PCSK7 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur PCSK7

Antigène: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Autre désignation: PCSK7 (PCSK7 Produits)

Synonymes: anticorps PC7, anticorps PCSK7, anticorps lpc, anticorps pc7, anticorps pc8, anticorps spc7, anticorps MGC115258, anticorps wu:fj05c03, anticorps zgc:158336, anticorps LPC, anticorps PC8, anticorps SPC7, anticorps AA959856, anticorps proprotein convertase subtilisin/kexin type 7, anticorps proprotein convertase subtilisin/kexin type 7 L homeolog, anticorps PCSK7, anticorps pcsk7.L, anticorps pcsk7, anticorps Pcsk7

Sujet: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart.

Poids moléculaire: 86247

ID gène: 9159

NCBI Accession: NP_004707

UniProt: Q16549