TBPL1 anticorps

N° du produit ABIN6655376

Détail du produit anti-TBPL1 anticorps

Antigène: TBPL1 (TBP-Like 1 (TBPL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TBPL1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Chromatin Immunoprecipitation (ChIP), Fluorescence Microscopy (FM)

Purification: Anti-TRF2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TRF2 from Human, Mouse, Muntjac (deer), and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TRF2 from other sources has not been determined.

Immunogène:

Immunogen: TRF2 Antibody was produced in mice by repeated immunizations with a full-length TRF2 human protein.

Immunogen Type: Recombinant Protein

Clone: 4A794-15

Isotype: IgG1

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 5 μg/mL

Application Note: Anti-TRF2 Antibody is suitable for use in ChIP, ELISA, Flow (Intracellular) Cytometry, IF/ICC, IHC (frozen), IP, and WB. Expect a band approximately 55.6 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

ChIP Dilution: User Optimized

Immunoprecipitation Dilution: 2 μg/10^6 cells

ELISA Dilution: 2 μg/mL

Flow Cytometry Dilution: User Optimized

Western Blot Dilution: 2-4 μg/mL

IF Microscopy Dilution: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur TBPL1

Antigène: TBPL1 (TBP-Like 1 (TBPL1))

Autre désignation: TRF2 (TBPL1 Produits)

Synonymes: anticorps MGC:8389, anticorps MGC:9620, anticorps STUD, anticorps TLF, anticorps TLP, anticorps TRF2, anticorps tlf, anticorps 4732475G08, anticorps AW011832, anticorps AW491032, anticorps D18347, anticorps STD, anticorps TRP, anticorps Tlp, anticorps tlp, anticorps trf, anticorps trf2, anticorps trp, anticorps zgc:92340, anticorps TATA binding protein 1, anticorps TFIID-1, anticorps TRANSCRIPTION FACTOR IID-1, anticorps TATA-box binding protein like 1, anticorps TATA-binding protein 1, anticorps TATA-box binding protein like 1 L homeolog, anticorps TATA box binding protein-like 1, anticorps TBP-like 1, anticorps TATA binding protein 1, anticorps TBPL1, anticorps tbp1, anticorps tbpl1.L, anticorps tbpl1, anticorps Tbpl1, anticorps TBP1

Sujet:

Synonyms: TRBF2, TRF2, Telomeric repeat-binding factor 2, TTAGGG repeat-binding factor 2, Telomeric DNA-binding protein

Background: TRF2 antibody detects human, mouse, deer and rat TRF2. TRF2 is an ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types. Anti TRF2 antibody is ideal for investigators involved in apoptosis and chromatin research.

Gene Name: TERF2

ID gène: 7014

NCBI Accession: NP_005643

UniProt: Q15554