CXCR6 anticorps (Chemokine (C-X-C Motif) Receptor 6) (N-Term) Primary Antibody
- Cet anticorp CXCR6 est non-conjugé
- ELISA, Fluorescence Microscopy (FM), Immunohistochemistry (IHC), Western Blotting (WB)
- Réactivité croisée (Details)
- Cross reactivity with Bonzo from other sources has not been determined.
- Anti-Bonzo Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography.
Immunogen: Anti-Bonzo antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the N-terminus of human Bonzo/STRL33. The sequence of. This peptide differs from those of African green monkey and pig-tailed macaque by one or two amino acids, respectively,.
Immunogen Type: Peptide
- Indications d'application
Immunohistochemistry Dilution: 20 μg/mL
Application Note: Anti-Bonzo Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 39 kDa in Western Blots of specific cell lysates and tissues.
ELISA Dilution: 1:5,000
Western Blot Dilution: 0.5 μg/mL
IF Microscopy Dilution: 20 μg/mL
- For Research Use only
Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Autre désignation
- Bonzo (CXCR6 Antibody Extrait)
Synonyms: Bonzo Antibody, BONZO, CD186, STRL33, TYMSTR, BONZO, C-X-C chemokine receptor type 6, CDw186, CXC-R6
Background: Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor. Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.
Gene Name: CXCR6
- ID gène