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Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12) (N-Term) anticorps Primary Antibody

PRSS12 Reactivité: Humain ELISA, FM, IHC, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6656954
$379.00
Plus frais de port $45.00 et $24.00 pour carboglace
100 μg
local_shipping Destination: Etats-Unis
Envoi sous 1 à 2 jours ouvrables
  • Antigène
    Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12)
    Épitope
    N-Term
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivité
    Humain
    • 17
    • 5
    • 4
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Conjugué
    Inconjugué
    • 15
    • 1
    • 1
    • 1
    Application
    ELISA, Fluorescence Microscopy (FM), Immunohistochemistry (IHC), Western Blotting (WB)
    • 12
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Réactivité croisée (Details)
    Cross reactivity with Neurotrypsin from other sources has not been determined.
    Purification
    Anti-Neurotrypsin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography.
    Immunogène

    Immunogen: Anti-Neurotrypsin antibody was prepared from whole rabbit serum produced by repeated immunizations with a 23 amino acid synthetic peptide from near the N-terminus of human neurotrypsin.

    Immunogen Type: Peptide

    Isotype
    IgG
  • Indications d'application

    Immunohistochemistry Dilution: 2.5 μg/mL

    Application Note: Anti-Neurotrypsin Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 97 kDa in Western Blots of specific cell lysates and tissues.

    ELISA Dilution: 1:5,000-1:20,000

    Western Blot Dilution: .5-2 μg/mL

    IF Microscopy Dilution: 20 μg/mL

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Antigène
    Protease, serine, 12 (Neurotrypsin, Motopsin) (PRSS12)
    Autre désignation
    Neurotrypsin (PRSS12 Antibody Extrait)
    Synonymes
    PRSS12, BSSP-3, BSSP3, MRT1, Bssp-3, motopsin, Nt, protease, serine 12, 26S proteasome regulatory SU, prsS12, neurotrypsin, protease, serine 12 neurotrypsin (motopsin), PRSS12, prsS12, HAN_3g451, CpipJ_CPIJ005457, CpipJ_CPIJ005852, Prss12
    Sujet

    Synonyms: Neurotrypsin Antibody, MRT1, BSSP3, BSSP-3, Neurotrypsin, Leydin

    Background: Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.

    Gene Name: PRSS12

    ID gène
    8492
    UniProt
    P56730
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