Retinoid X Receptor gamma anticorps

N° du produit ABIN6657359

Détail du produit anti-Retinoid X Receptor gamma anticorps

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoid X Receptor gamma est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Rat (Rattus)

Réactivité croisée (Details): Cross reactivity to other sources has not been tested.

Purification: Anti-Retinoic Acid Receptor gamma antibody detects Retinoic Acid Receptor gamma. Retinoic Acid Receptor gamma antibody was Protein G purified. This antibody is directed against human retinoic acid receptor gamma protein. Reactivity is expected from the following species based on 100% sequence homology: bovine, mouse, non-human primate and rat.

Immunogène:

Immunogen: Anti-Retinoic Acid Receptor gamma was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the hinged region of RAR-gamma.

Immunogen Type: Peptide

Clone: 1373

Isotype: IgG1

Information d'application

Indications d'application:

Application Note: Anti-Retinoid X Receptor gamma antibody is suitable for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to the RXR-γ isotype in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Détails sur Retinoid X Receptor gamma

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Autre désignation: Retinoid X Receptor gamma (RXRG Produits)

Synonymes: anticorps NR2B3, anticorps RXRC, anticorps zgc:92183, anticorps RXRgamma, anticorps RXRG, anticorps RXR-gamma, anticorps nr2b3, anticorps xrxrg, anticorps rxrc, anticorps Nr2b3, anticorps NR2B1, anticorps RXR, anticorps rxra, anticorps rxrg, anticorps retinoid X receptor gamma, anticorps retinoid X receptor, gamma b, anticorps retinoid X receptor gamma L homeolog, anticorps retinoid x receptor, gamma a, anticorps RXRG, anticorps rxrgb, anticorps rxrg.L, anticorps rxrg, anticorps Rxrg, anticorps RXRGAMMA, anticorps rxrga

Sujet:

Synonyms: mouse anti-Retinoid X Receptor gamma Antibody, mouse anti-RXRG antibody, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma

Background: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Gene Name: RXRG

ID gène: 6258

UniProt: P48443

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway