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ABCB11 anticorps (C-Term)

ABCB11 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6657515
  • Antigène Voir toutes ABCB11 Anticorps
    ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
    Épitope
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 29
    • 4
    Lapin
    Clonalité
    • 29
    • 4
    Polyclonal
    Conjugué
    • 19
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ABCB11 est non-conjugé
    Application
    • 19
    • 12
    • 11
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Purification
    Anti-ABCB11 antibody is directed against human ABCB11 protein.  The product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on homology for the immunogen sequence.  Cross reactivity with ABCB11 from other sources has not been determined.
    Immunogène

    Immunogen: ABCB11 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human ABCB11, different from the related mouse and rat sequences by three amino acids.

    Immunogen Type: Peptide

    Isotype
    IgG
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    Discover our top product ABCB11 Anticorps primaire
  • Indications d'application

    Immunohistochemistry Dilution: 0.5-1 μg/mL

    Application Note: Anti-ABCB11 Antibody is useful for Immunohistochemistry -P and Western Blotting. Positive control rat liver, mouse liver, and SMMC whole cell lysate used at 40 μg load and 0.5 μg/mL incubation in western blot and rat mouse, and human liver tissue for IHC-P. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~146.4 kDa corresponding to the appropriate cell lysate or extract.

    Western Blot Dilution: 0.1-0.5 μg/mL

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution

    Reconstitution Volume: 200μL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    Buffer

    Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

    Stabilizer: 5 mg BSA

    0.05 mg Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Antigène
    ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
    Autre désignation
    ABCB11 (ABCB11 Produits)
    Synonymes
    anticorps ABCB11, anticorps Bsep, anticorps ABC16, anticorps BRIC2, anticorps BSEP, anticorps PFIC-2, anticorps PFIC2, anticorps PGY4, anticorps SPGP, anticorps Lith1, anticorps BSEP/SPGP, anticorps Spgp, anticorps ATP binding cassette subfamily B member 11, anticorps bile salt export pump, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 11, anticorps ABCB11, anticorps LOC100489744, anticorps LOC100565276, anticorps EDI_111220, anticorps EDI_272930, anticorps abcb11, anticorps Abcb11
    Sujet

    Synonyms: ATP-binding cassette sub-family B member 11, BSEP, Bile Salt Export Pump

    Background: Bile Salt Export Pump (BSEP) is a protein which in humans is encoded by the ABCB 11 gene. It is a member of the superfamily of ATP-binding cassette (ABC) transporters, also known as ABCB11. It is mapped to chromosome 2q24. The BSEP protein is mainly expressed in the liver. ABCB11 is a gene associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) which caused by mutations in the ABCB11 gene will increases the risk of hepatocellular carcinoma in early life. This antibody is suitable for researchers interested in signal transduction and cancer research.

    Gene Name: ABCB11

    ID gène
    8647
    NCBI Accession
    NP_003733
    UniProt
    O95342
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