beta Amyloid anticorps (C-Term)

N° du produit ABIN6658203

Détail du produit anti-beta Amyloid anticorps

Antigène: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Épitope: C-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp beta Amyloid est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): Cross reactivity with beta amyloid from other species has not been determined

Purification: Anti-Beta Amyloid Antibody is directed against rat Beta Amyloid proteins. The antibody is directed against rat Beta Amyloid. Anti-Beta Amyloid antibody was affinity purified from monospecific antiserum by immunoaffinity purification. . However, reactivity is also expected from the following species based on 100% sequence homology: canine, chicken, human, mouse and non-human primate.

Immunogène:

Immunogen: Anti-Beta Amyloid Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region.

Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: Anti-Beta Amyloid antibody is suitable for use in ELISA, Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 115 kDa in size corresponding to the APP protein in the appropriate cell lysate or extract.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Détails sur beta Amyloid

Antigène: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Autre désignation: Beta Amyloid (Abeta Produits)

Synonymes: anticorps AAA, anticorps ABETA, anticorps ABPP, anticorps AD1, anticorps APPI, anticorps CTFgamma, anticorps CVAP, anticorps PN-II, anticorps PN2, anticorps aaa, anticorps abeta, anticorps abpp, anticorps ad1, anticorps appi, anticorps ctfgamma, anticorps cvap, anticorps pn2, anticorps Abeta, anticorps Abpp, anticorps Adap, anticorps Ag, anticorps Cvap, anticorps E030013M08Rik, anticorps betaApp, anticorps amyloid beta precursor protein, anticorps amyloid beta (A4) precursor protein, anticorps APP, anticorps app, anticorps App

Sujet:

Synonyms: Amyloid beta A4 protein, ABPP, Alzheimer disease amyloid A4 protein homolog, Amyloidogenic glycoprotein, A-beta, ABeta antibody

Background: Anti-Beta Amyloid antibody recognizes beta amyloid protein also called amyloid precursor protein (APP). A large body of evidence has implicated the APP in the pathogenesis of Alzheimer's disease (AD). The phosphorylation of APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD. Anti-Beta Amyloid antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: APP

ID gène: 54226

UniProt: P08592

Pathways: Inflammasome