TSG101 anticorps (Tumor Susceptibility Gene 101)

Details for Product anti-TSG101 Antibody No. ABIN6674283
Antigène
Reactivité
Humain, Souris, Rat (Rattus)
124
57
47
12
10
8
8
8
6
6
5
4
3
2
1
1
Hôte
Lapin
113
15
Clonalité
Polyclonal
Conjugué
Cet anticorp TSG101 est non-conjugé
8
5
4
4
4
4
3
3
3
3
3
3
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
109
62
50
20
15
12
7
3
3
3
3
2
1
1
1
Options
Immunogène Fusion protein of human TSG101
Isotype IgG
Purification Affinity purification
Antigène
Autre désignation TSG101 (TSG101 Antibody Extrait)
Sujet The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
Synonyms: TSG10, VPS23
ID gène 7251
UniProt Q99816
Indications d'application Recommended dilutions: WB: 1:500-1:1000, IHC: 1:50-1:100, IF: 1:20-1:50
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid freeze / thaw cycles
Stock -20 °C,-80 °C
Stockage commentaire

Storage: -20 °C/-80 °C

Images (Fournisseur)
Image no. 1 for anti-Tumor Susceptibility Gene 101 (TSG101) antibody (ABIN6674283) Western blot analysis of extracts of Hela cell line, using TSG101 antibody.
Produit citée dans: Zhao, Wu, Duan, Ma, Shen, Wei, Cui, Zhang, Xie, Liu: "Quantitative proteomic analysis of exosome protein content changes induced by hepatitis B virus in Huh-7 cells using SILAC labeling and LC-MS/MS." dans: Journal of proteome research, Vol. 13, Issue 12, pp. 5391-402, 2015 (PubMed). Méthode utilisée: Western Blotting (WB)

Yu, Yan, Yang, Wu, Ling, Chen, Tang, Tan, Cao, Wu, Yan, Wang: "Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein." dans: Nature communications, Vol. 5, pp. 5256, 2014 (PubMed). Méthode utilisée: Western Blotting (WB)