NREP anticorps (AA 25-68)

N° du produit ABIN668496

Détail du produit anti-NREP anticorps

Antigène: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Épitope: AA 25-68

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NREP est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human P311

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-NREP (ABIN668496)

Li, Yao, He, Gao, Bai, Yang, Zhang, Zhan, Tan, Zhou, Takata, Wu, Luo: "P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression." dans: Stem cell research & therapy, Vol. 7, Issue 1, pp. 175, (2016) (PubMed).

Yao, Li, He, Yang, Zhang, Zhan, Xu, Tan, Zhou, Wu, Luo: "P311 Accelerates Skin Wound Reepithelialization by Promoting Epidermal Stem Cell Migration Through RhoA and Rac1 Activation." dans: Stem cells and development, Vol. 26, Issue 6, pp. 451-460, (2016) (PubMed).

Yao, Yang, He, Li, Xu, Zhang, Li, Zhan, Sun, Tan, Zhou, Luo, Wu: "P311 promotes renal fibrosis via TGFβ1/Smad signaling." dans: Scientific reports, Vol. 5, pp. 17032, (2015) (PubMed).

Yan, Zhang, Wang, Xu, Ren, Zhang, Shi, Chen, Shi, Tian, Zhao, Dong: "Significant reduction of the GLUT3 level, but not GLUT1 level, was observed in the brain tissues of several scrapie experimental animals and scrapie-infected cell lines." dans: Molecular neurobiology, Vol. 49, Issue 2, pp. 991-1004, (2014) (PubMed).

Peng, Yuan, Tan, Ma, Bian, Xu, He, Cao, Huang, Cui, Gan, Wang, Zhou, Hu, Yang, Luo, Wu: "Identification of ITGB4BP as a new interaction protein of P311." dans: Life sciences, Vol. 90, Issue 15-16, pp. 585-90, (2012) (PubMed).

Détails sur NREP

Antigène: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Autre désignation: P311 protein (C5orf13 Produits)

Synonymes: anticorps 3.1, anticorps CZH5orf13, anticorps NREP, anticorps C5orf13, anticorps D4S114, anticorps P311, anticorps PRO1873, anticorps PTZ17, anticorps SEZ17, anticorps AI325076, anticorps D0H4S114, anticorps Harp, anticorps neuronal regeneration related protein, anticorps NREP, anticorps Nrep

Sujet:

Synonyms: P311, PTZ17, SEZ17, D4S114, C5orf13, PRO1873, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311, NREP

Background: May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3 (By similarity). May play a role in the regulation of alveolar generation.

ID gène: 9315

UniProt: Q16612