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WNK4 anticorps (AA 351-450)

WNK4 Reactivité: Souris ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN668526
  • Antigène Voir toutes WNK4 Anticorps
    WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
    Épitope
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivité
    • 46
    • 29
    • 26
    • 4
    • 1
    Souris
    Hôte
    • 46
    • 2
    Lapin
    Clonalité
    • 46
    • 2
    Polyclonal
    Conjugué
    • 12
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WNK4 est non-conjugé
    Application
    • 27
    • 25
    • 8
    • 1
    ELISA, Western Blotting (WB)
     Réactivité croisée
    Souris
    Homologie
    Human,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human WNK4
    Isotype
    IgG
    Top Product
    Discover our top product WNK4 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
    Autre désignation
    WNK4 (WNK4 Produits)
    Synonymes
    anticorps WNK4, anticorps PHA2B, anticorps PRKWNK4, anticorps 2010002J11Rik, anticorps Pha2b, anticorps Prkwnk4, anticorps Ac2-059, anticorps WNK lysine deficient protein kinase 4, anticorps WNK4, anticorps Wnk4
    Sujet

    Synonyms: PHA 2B, PHA2B, PRKWNK 4, PRKWNK4, Protein kinase lysine deficient 4, Protein kinase with no lysine 4, Serine/threonine protein kinase WNK4, WNK lysine deficient protein kinase 4, WNK4_HUMAN.

    Background: Regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation which appears to prevent membrane trafficking of SLC12A3. Also inhibits the renal K(+)channel, KCNJ1, via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis. WNK4 appears to act as a molecular switch that can vary the balance between NaCl reabsorption and K(+)secretion to maintain integrated homeostasis.

    ID gène
    65266
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