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CD31 anticorps (AA 601-680)

PECAM1 Reactivité: Humain, Souris, Rat, Lapin, Porc, Chien FACS, WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN669006
  • Antigène Voir toutes CD31 (PECAM1) Anticorps
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Épitope
    • 18
    • 16
    • 15
    • 12
    • 8
    • 8
    • 7
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-680
    Reactivité
    • 274
    • 141
    • 71
    • 58
    • 41
    • 28
    • 21
    • 18
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Lapin, Porc, Chien
    Hôte
    • 159
    • 147
    • 48
    • 7
    • 3
    • 2
    Lapin
    Clonalité
    • 233
    • 132
    • 1
    Polyclonal
    Conjugué
    • 156
    • 33
    • 33
    • 24
    • 11
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD31 est non-conjugé
    Application
    • 227
    • 185
    • 97
    • 88
    • 62
    • 37
    • 36
    • 33
    • 25
    • 25
    • 21
    • 15
    • 13
    • 9
    • 6
    • 5
    • 4
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    • 3
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
     Réactivité croisée
    Chien, Humain, Souris, Porc, Lapin, Rat
    Homologie
    Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from mouse CD31
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Li, Zhang, Chen, Tian, Wang: "Increased Angiogenic and Adipogenic Differentiation Potentials in Adipose-Derived Stromal Cells from Thigh Subcutaneous Adipose Depots Compared with Cells from the Abdomen." dans: Aesthetic surgery journal, Vol. 39, Issue 5, pp. NP140-NP149, (2019) (PubMed).

    Vuletic, Zhou, Li, Bai, Meng, Zhu, Ding, Li, Sun, Ren: "Validation of Bevacizumab Therapy Effect on Colon Cancer Subtypes by Using Whole Body Imaging in Mice." dans: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, (2017) (PubMed).

    Long, Lankford, Kumar, Grahn, Borjesson, Farmer, Wang: "Isolation and characterization of canine placenta-derived mesenchymal stromal cells for the treatment of neurological disorders in dogs." dans: Cytometry. Part A : the journal of the International Society for Analytical Cytology, Vol. 93, Issue 1, pp. 82-92, (2017) (PubMed).

    Korkmaz, Ulrich, Vogels, de Wit, van Zuijlen, Krijnen, Niessen: "Neutrophil extracellular traps coincide with a pro-coagulant status of microcirculatory endothelium in burn wounds." dans: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, Vol. 25, Issue 4, pp. 609-617, (2017) (PubMed).

    Zhang, Chen, Liu, Zhou, Hu, Zhou, Han, Chen: "Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways." dans: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 5, pp. 598-606, (2016) (PubMed).

    Guo, Wang, Qiao, Yang, Su, Gao, Xu: "A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord." dans: Molecular neurobiology, (2015) (PubMed).

    Zhou, Yang, Xin, Zhang, Hu, Zhou, Chen, Chen et al.: "Exendin-4 enhances the migration of adipose-derived stem cells to neonatal rat ventricular cardiomyocyte-derived conditioned medium via the phosphoinositide 3-kinase/Akt-stromal cell-derived ..." dans: Molecular medicine reports, (2015) (PubMed).

    Wang, Wang, Fang, Zhou, Liu, Su: "High glucose induces and activates Toll-like receptor 4 in endothelial cells of diabetic retinopathy." dans: Diabetology & metabolic syndrome, Vol. 7, pp. 89, (2015) (PubMed).

    Yu, Wang, Wang, Lu, Li, Qin, Huang: "Activation of liver X receptor enhances the proliferation and migration of endothelial progenitor cells and promotes vascular repair through PI3K/Akt/eNOS signaling pathway activation." dans: Vascular pharmacology, Vol. 62, Issue 3, pp. 150-61, (2014) (PubMed).

    Rossmeisl, Garcia, Roberston, Ellis, Davalos: "Pathology of non-thermal irreversible electroporation (N-TIRE)-induced ablation of the canine brain." dans: Journal of veterinary science, Vol. 14, Issue 4, pp. 433-40, (2014) (PubMed).

    Zeng, Zhang, Li, Yang, Chen, Liu: "A new method to isolate and culture rat kupffer cells." dans: PLoS ONE, Vol. 8, Issue 8, pp. e70832, (2013) (PubMed).

    Yuan, Huang, Chu, Li, Li, Si: "A targeted high-efficiency angiogenesis strategy as therapy for myocardial infarction." dans: Life sciences, Vol. 90, Issue 17-18, pp. 695-702, (2012) (PubMed).

    Yuan, Huang, Chu, Li, Si: "A visible, targeted high-efficiency gene delivery and transfection strategy." dans: BMC biotechnology, Vol. 11, pp. 56, (2011) (PubMed).

    Zhang, Huang, Wu, Yang, Song, Chen, Fan, Wang: "Cardiac stem cells differentiate into sinus node-like cells." dans: The Tohoku journal of experimental medicine, Vol. 222, Issue 2, pp. 113-20, (2010) (PubMed).

    Chen, Lin, Kanekura, Su, Lin, Xie, Wu, Li, Chen, Chang: "A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma." dans: Cancer research, Vol. 66, Issue 23, pp. 11323-30, (2006) (PubMed).

  • Antigène
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Autre désignation
    CD31 (PECAM1 Produits)
    Synonymes
    anticorps CD31, anticorps CD31/EndoCAM, anticorps GPIIA', anticorps PECA1, anticorps PECAM-1, anticorps endoCAM, anticorps C85791, anticorps Cd31, anticorps Pecam, anticorps platelet/endothelial cell adhesion molecule 1, anticorps platelet and endothelial cell adhesion molecule 1, anticorps pecam1, anticorps PECAM1, anticorps Pecam1
    Sujet

    Synonyms: CD31, PECA1, GPIIA', PECAM-1, endoCAM, CD31/EndoCAM, Platelet endothelial cell adhesion molecule, PECAM1

    Background: Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-69 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).

    ID gène
    5175
    UniProt
    P16284
    Pathways
    Regulation of Actin Filament Polymerization
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