RAB7A anticorps

N° du produit ABIN6699197

Détail du produit anti-RAB7A anticorps

Antigène: RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB7A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Anti-Rab-7 Antibody was purified by peptide affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Rab-7 from rat and New World monkey based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Rab-7 from other sources has not been determined.

Immunogène:

Immunogen: Rab-7 Antibody was produced from whole rabbit serum prepared by repeated immunizations at the internal amino acids of human Rab-7 protein.

Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 10 μg/mL (paraffin)

Application Note: Anti-Rab7 antibody is suitable for use in IHC (p) and WB. Expect a band approximately 23 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Détails sur RAB7A

Antigène: RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))

Autre désignation: Rab-7 (RAB7A Produits)

Synonymes: anticorps RAB5, anticorps PRO2706, anticorps RAB7, anticorps Rab7, anticorps rab7, anticorps pro2706, anticorps RAB7A, anticorps LOC100231734, anticorps ARABIDOPSIS RAB GTPASE HOMOLOG G2, anticorps ATRAB7A, anticorps ATRABG2, anticorps F7D8.20, anticorps F7D8_20, anticorps RAB GTPase homolog 7A, anticorps DDBDRAFT_0190210, anticorps DDBDRAFT_0191507, anticorps DDB_0190210, anticorps DDB_0191507, anticorps Rab7a, anticorps rab-7, anticorps zgc:64058, anticorps RAB5A, member RAS oncogene family, anticorps RAB7A, member RAS oncogene family, anticorps RAB7A, member RAS oncogene family L homeolog, anticorps rab7A protein, anticorps RAB GTPase homolog 7A, anticorps Rab GTPase, anticorps ras-related protein rab-7a, anticorps RAB7, member RAS oncogene family, anticorps RAB5A, anticorps RAB7A, anticorps Rab7a, anticorps rab7a.L, anticorps rab7a, anticorps rab7A, anticorps Rab7, anticorps rab7

Sujet:

Synonyms: RAB7, Ras-related protein Rab-7a

Background: Anti-Rab7 antibody detects human Rab7. Rab7 is a 207 amino acid transport carrier, belonging to the Rab family of RAS-related GTP-binding proteins with 4 GTP/GDP-binding sites and terminates in sequences such as cys-X-cys, cys-cys or a closely related sequence. Rab7 located in specific intracellular compartments is known to be an important regulator of vesicular transport of proteins from early to late endosomes and lysosome biogenesis. Rab7 accelerates thyroid hormone production controlling aggregation and fusion of late lysosomes. It is ubiquitously expressed in most of the tissues and plays an essential role in maintenance of the perinuclear lysosome compartment. Anti-Rab7 antibody is ideal for investigators involved in caner, NFkappaB , and signaling research, kinase and phosphatase protein research.

Gene Name: RAB7A

ID gène: 7879

NCBI Accession: NP_004628

UniProt: P51149

Pathways: EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome