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Nuclear Pore Complex anticorps

Reactivité: Saccharomyces cerevisiae FM Hôte: Souris Monoclonal 39C7 unconjugated
N° du produit ABIN6699198
  • Antigène
    Nuclear Pore Complex
    Reactivité
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Saccharomyces cerevisiae
    Hôte
    • 4
    Souris
    Clonalité
    • 4
    Monoclonal
    Conjugué
    • 4
    Inconjugué
    Application
    • 2
    • 2
    • 2
    • 1
    • 1
    Fluorescence Microscopy (FM)
     Réactivité croisée
    Humain, Souris, Rat (Rattus)
    Purification
    Anti-Nuclear Pore Complex antibody is directed against Nuclear Pore Complex proteins. The antibody is protein G purified from concentrated clarified cell culture supernate. This antibody is directed against yeast NPC protein. Reactivity is expected from human, mouse and rat.
    Immunogène

    Immunogen: Anti-Nuclear Pore Complex Antibody (Monoclonal) was produced by repeated immunizations with yeast nuclear preparations.

    Immunogen Type: Native Protein

    Clone
    39C7
    Isotype
    IgG
  • Indications d'application

    Application Note: Anti-Nuclear Pore Complex Antibody is suitable for use in IF. Specific conditions for reactivity should be optimized by the end user

    IF Microscopy Dilution: 1:50-100

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.20.01 % (w/v) Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
  • Antigène
    Nuclear Pore Complex
    Sujet

    Synonyms: mouse anti-Nuclear Pore Complex Antibody, NPC, NUP62, NUP, NUP133

    Background: Nuclear Pore Complex Antibodydetects Nuclear Pore Complex proteins. The nuclear pore complex (NPC) is a very large structure made up of at least 50 different proteins that span the double membrane of the nuclear envelope functioning as a gateway for macromolecular traffic between the cytoplasm and the nucleus. Discrete nuclear pore complex proteins or nucleoporins such as NUP98, NUP180 and p62 have been implicated in autoimmune disease and cancer. Patients with primary biliary cirrhosis (PBC) frequently produce autoantibodies against p62 and NUP180 while NUP98 translocations have been found in patients with acute myelogenous leukemia (AML). Anti-Nuclear Pore Complex Antibody is ideal for investigators involved in Cancer and Immunology Research.

    Gene Name: Nuclear stain of multiple gene products including Nup62, Nup133

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