ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) (AA 21-100) anticorps

N° du produit ABIN670161

Détail du produit

Antigène: ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B)

Épitope: AA 21-100

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse MDR1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Référence

Wei, Liang, Junsong, Rui, Shuai, Guanglin, Shicai, Zexing, Jin, Xiangming, Shufeng: "The impact of insulin on chemotherapeutic sensitivity to 5-fluorouracil in gastric cancer cell lines SGC7901, MKN45 and MKN28." dans: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 64, (2016) (PubMed).

Sun, Jiao, Chen, Liu, Zhao: "MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1." dans: Journal of ovarian research, Vol. 8, pp. 80, (2016) (PubMed).

Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." dans: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

Détail du antigène

Antigène: ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B)

Autre désignation: MDR1 (ABCB1B Produits)

Synonymes: anticorps ABC20, anticorps CD243, anticorps CLCS, anticorps GP170, anticorps MDR1, anticorps P-GP, anticorps PGY1, anticorps Abcb1, anticorps Mdr1, anticorps Mdr1b, anticorps Pgy-1, anticorps Pgy1, anticorps mdr, anticorps ATP binding cassette subfamily B member 1, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 1B, anticorps ATP-binding cassette, subfamily B (MDR/TAP), member 1B, anticorps ABCB1, anticorps Abcb1b

Sujet:

Synonyms: Pgp, P-gp, Evi32, Mdr1a, Multidrug resistance protein 1A, ATP-binding cassette sub-family B member 1A, Abcb1a

Background: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

ID gène: 18671

UniProt: P21447