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Collagen, Type I (COL1) (AA 1350-1400) anticorps Primary Antibody

COL1 Reactivité: Humain, Souris, Rat IF (p), IHC (p) Hôte: Lapin Polyclonal
Pubmed (16)
N° du produit ABIN670386
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Destination: Etats-Unis
Envoi sous 4 à 6 jours ouvrables
  • Antigène
    Épitope
    AA 1350-1400
    Reactivité
    Humain, Souris, Rat
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Conjugué
    Inconjugué
    Application
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody is produced using a peptide that is found in the C-terminal propeptide region.
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Collagen I
    Isotype
    IgG
  • Indications d'application
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C
    Date de péremption
    12 months
  • Yang, Shi, Wu, Li, Zhang, Li, Zhai, Jia, Dang: "Caffeic acid phenethyl ester up-regulates antioxidant levels in hepatic stellate cell line T6 via an Nrf2-mediated mitogen activated protein kinases pathway." dans: World journal of gastroenterology, Vol. 23, Issue 7, pp. 1203-1214, 2017 (PubMed). Méthode utilisée: Western Blotting (WB) (Échantillon (espèces): Rat (Rattus)).

    Tian, Li, Yang, Luo, Dai, Liu, Song, Zhang: "Orally administered simvastatin partially preserves lumbar vertebral bone mass but not integrity of intervertebral discs in ovariectomized rats." dans: Experimental and therapeutic medicine, Vol. 13, Issue 3, pp. 877-884, 2017 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rat (Rattus)). Détails: Sample: lumbar spine

    Yu, Liu, Sun, Wang, Wang, Zhao, Dai, Zhao, Zhang, Li, Han, Lu, Dong, Liu, Yu, Li: "Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway." dans: Oncotarget, Vol. 8, Issue 23, pp. 37705-37716, 2017 (PubMed). Méthode utilisée: Western Blotting (WB) (Échantillon (espèces): Dog (Canine)). Détails: Sample: heart

    Yang, Zhao, Wang, Liu, Ma, Huang, Liu: "Isolation and biological characterization of tendon-derived stem cells from fetal bovine." dans: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 8, pp. 846-56, 2017 (PubMed). Méthode utilisée: Immunofluorescence (Cultured Cells) (IF (cc))

    Long, Luo, Wang, Bates, Shetty: "Mash1-dependent Notch Signaling Pathway Regulates GABAergic Neuron-Like Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells." dans: Aging and disease, Vol. 8, Issue 3, pp. 301-313, 2017 (PubMed). Méthode utilisée: Flow Cytometry (FACS)

    Çakir-Özkan, Bereket, Sener, Alici, Kabak, Önger: "Therapeutic Effects of Sildenafil on Experimental Mandibular Fractures." dans: The Journal of craniofacial surgery, Vol. 27, Issue 3, pp. 615-20, 2016 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rat (Rattus)). Détails: Sample: hemimandibles

    Wang, Yang, Lin, Liu, Yang, Kuo, Chen: "Expandable Scaffold Improves Integration of Tissue-Engineered Cartilage: An In Vivo Study in a Rabbit Model." dans: Tissue engineering. Part A, Vol. 22, Issue 11-12, pp. 873-84, 2016 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rabbit). Détails: Sample: engineered cartilage

    Cecen, Kozaci, Yuksel, Ustun, Ergur, Havitcioglu: "Biocompatibility and biomechanical characteristics of loofah based scaffolds combined with hydroxyapatite, cellulose, poly-l-lactic acid with chondrocyte-like cells." dans: Materials science & engineering. C, Materials for biological applications, Vol. 69, pp. 437-46, 2016 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Human).

    Wang, Li, Huang, Wang: "The influence of hypoxia during different pregnancy stages on cardiac collagen accumulation in the adult offspring." dans: BioMed research international, Vol. 2014, pp. 419805, 2015 (PubMed). Méthode utilisée: Western Blotting (WB)

    Zhou, Wang, Song, He, He, He: "Antihypertensive and vascular remodelling effects of the imperatorin derivative OW1 in renovascular hypertension rats." dans: Clinical and experimental pharmacology & physiology, Vol. 41, Issue 8, pp. 571-8, 2014 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rat (Rattus)). Détails: Sample: Kidney

    McNary, Athanasiou, Reddi: "Transforming growth factor β-induced superficial zone protein accumulation in the surface zone of articular cartilage is dependent on the cytoskeleton." dans: Tissue engineering. Part A, Vol. 20, Issue 5-6, pp. 921-9, 2014 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rabbit). Détails: Sample: articular chondrocytes

    Luo, Zhang, Wang, Hu, Song, Su, Zhang: "Alendronate retards the progression of lumbar intervertebral disc degeneration in ovariectomized rats." dans: Bone, Vol. 55, Issue 2, pp. 439-48, 2013 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Rat (Rattus)). Détails: Sample: annulus fibrosus

    Guo, Li, Dong, Chen, Deng, Wang, Ying: "Piezoelectric PU/PVDF electrospun scaffolds for wound healing applications." dans: Colloids and surfaces. B, Biointerfaces, Vol. 96, pp. 29-36, 2012 (PubMed). Méthode utilisée: Western Blotting (WB) (Échantillon (espèces): Mouse (Murine)).

    Zhang, Ma, Xi, Zhang, Li: "Administration of a novel penicillamine-bound membrane: a preventive and therapeutic treatment for abdominal adhesions." dans: BMC surgery, Vol. 11, pp. 5, 2011 (PubMed). (Échantillon (espèces): Rat (Rattus)). Détails: Sample: adhesions tissue inside theabdominal cavity

    Xu, Chen, Huang, Varghese, Moorhead, Yan, Powis, Li, Ruan: "Inflammatory stress exacerbates lipid-mediated renal injury in ApoE/CD36/SRA triple knockout mice." dans: American journal of physiology. Renal physiology, Vol. 301, Issue 4, pp. F713-22, 2011 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Mouse (Murine)). Détails: Sample: kidney

    Yang, Yang, Tu, Zheng, Cai, Wang: "Strontium enhances osteogenic differentiation of mesenchymal stem cells and in vivo bone formation by activating Wnt/catenin signaling." dans: Stem cells (Dayton, Ohio), Vol. 29, Issue 6, pp. 981-91, 2011 (PubMed).

  • Antigène
    Autre désignation
    Collagen I
    Sujet

    This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008].

    Subcellular location: Extracellular

    Synonyms: Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1, Pro-collagen 1.

    Poids moléculaire
    161kDa
    ID gène
    1277
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