Vestigial Like 2 (Drosophila) (VGLL2) (AA 34-79) anticorps Primary Antibody
VGLL2 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal
N° du produit ABIN6711035
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- AA 34-79
- Humain, Souris, Rat
- Western Blotting (WB)
- VGLL2 polyclonal antibody detects endogenous levels of VGLL2 protein.
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- > 95% (by SDS-PAGE)
- Synthetic peptide, corresponding to amino acids 34-79 of Human VGLL2.
- Indications d'application
- WB: 1:500~1:1000
- For Research Use only
- 1 mg/mL
- 1 mg/mL in Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze-thaw cycles.
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term.
- Autre désignation
- VGLL2 (VGLL2 Antibody Extrait)
- vgll2a, MGC114146, zgc:114146, vgl-2, VGL2, VITO1, C130057C21Rik, VITO-1, Vito1, vestigial like family member 2, vestigial-like family member 2a, vestigial like family member 2 L homeolog, vestigial-like family member 2, VGLL2, vgll2a, vgll2.L, Vgll2
- Vgl-2 (Transcription cofactor vestigial-like protein 2), also known as VITO-1, is a 317 amino acid protein that contains a domain through which it interacts with TEF-1, a protein that plays a role in controlling the expression of numerous genes. Specific to skeletal muscle, Vgl-2 is expressed highly in adult fast muscle and is expressed at lower levels in adult slow muscle and fetal skeletal muscle. During muscle differentiation, Vgl-2 mRNA levels increase and Vgl-2 translocates from the cytoplasm to the nucleus.Overexpression of Vgl-2 in MYOD-transfected 10T1/2 mouse embryonic fibroblasts increases expression of myosin heavy chain (MHC), which is a marker of terminal muscle differentiation. This evidence suggests that Vgl-2 is essential for muscle gene expression. There are two isoforms of Vgl-2 that are produced as a result of alternative splicing events.
- Poids moléculaire
- ~ 33 kDa
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