Integrin alpha 4 (ITGA4) (AA 584-609) anticorps

N° du produit ABIN671301

Détail du produit

Antigène:

Integrin alpha 4 (ITGA4)

Épitope: AA 584-609

Reactivité: Humain, Souris, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Integrin alpha 4

Isotype: IgG

Information d'application

Indications d'application: WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C

Date de péremption: 12 months

Référence

Lee, Lee, Huang, Chang, Lin, Chien, Yang, Lin: "Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells." dans: PLoS ONE, Vol. 9, Issue 11, pp. e111390, 2014 (PubMed). (Échantillon (espèces): Rabbit).

Détail du antigène

Antigène:

Integrin alpha 4 (ITGA4)

Autre désignation: Integrin alpha 4/CD49d (ITGA4 Antibody Extrait)

Sujet:

Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

Subcellular location: Extracellular

Synonyms: IA4, CD49D, Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, VLA-4 subunit alpha, ITGA4

ID gène: 3676

UniProt: P13612

Pathways: Integrin Complex