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MRP1 anticorps (AA 501-600)

MRP1 Reactivité: Humain, Rat WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN671526
  • Antigène Voir toutes MRP1 Anticorps
    MRP1 (Macrophage Inflammatory Protein Related Protein 1 (MRP1))
    Épitope
    • 15
    • 1
    • 1
    • 1
    AA 501-600
    Reactivité
    • 27
    • 19
    • 5
    Humain, Rat
    Hôte
    • 28
    • 1
    • 1
    Lapin
    Clonalité
    • 22
    • 8
    Polyclonal
    Conjugué
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MRP1 est non-conjugé
    Application
    • 20
    • 13
    • 12
    • 12
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Rat
    Homologie
    Mouse,Cow,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from mouse MRP1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." dans: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

    Yan, Xie, Li, Zhang, Ma, Xie, Li, Zhong: "Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, (2013) (PubMed).

    Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

  • Antigène
    MRP1 (Macrophage Inflammatory Protein Related Protein 1 (MRP1))
    Autre désignation
    MRP1 (MRP1 Produits)
    Synonymes
    anticorps Abcc1a, anticorps Avcc1a, anticorps Mrp, anticorps Mrp1, anticorps BTCC-1, anticorps DRAP-27, anticorps MIC3, anticorps MRP-1, anticorps TSPAN-29, anticorps TSPAN29, anticorps Scya6, anticorps c10, anticorps ATP binding cassette subfamily C member 1, anticorps CD9 molecule, anticorps chemokine (C-C motif) ligand 6, anticorps Abcc1, anticorps CD9, anticorps Ccl6
    Sujet

    Synonyms: MRP, Mrp1, Mdrap, Abcc1a, Abcc1b, Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, LTC4 transporter, Abcc1

    Background: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

    ID gène
    17250
    UniProt
    O35379
    Pathways
    Response to Water Deprivation, Cell-Cell Junction Organization
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