ARPC1B anticorps (AA 293-372)

N° du produit ABIN6719390

Détail du produit anti-ARPC1B anticorps

Antigène: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Épitope: AA 293-372

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARPC1B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for ARP2/3 subunit 1B/ARPC1B detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for ARP2/3 subunit 1B/ARPC1B detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ARP2/3 subunit 1B/ARPC1B recombinant protein (Position: Q293-K372).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ARPC1B

Antigène: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Autre désignation: ARPC1B (ARPC1B Produits)

Synonymes: anticorps ARC41, anticorps p40-ARC, anticorps p41-ARC, anticorps cb871, anticorps arpc1a, anticorps fj15h02, anticorps zgc:64056, anticorps wu:fj08e12, anticorps wu:fj15h02, anticorps 41kDa, anticorps AA408064, anticorps AA408534, anticorps AA571392, anticorps AF007010, anticorps AW208418, anticorps L72, anticorps SOP2Hs, anticorps ACTIN-RELATED PROTEIN C1, anticorps ARPC1, anticorps F16D14.14, anticorps F16D14_14, anticorps actin-related protein C1B, anticorps arc41, anticorps p40-arc, anticorps p41-arc, anticorps actin related protein 2/3 complex subunit 1B, anticorps actin related protein 2/3 complex, subunit 1B, anticorps ARP2/3 complex 41 kDa subunit, anticorps actin-related protein C1B, anticorps actin-related protein 2/3 complex subunit 1B, anticorps actin related protein 2/3 complex subunit 1B S homeolog, anticorps ARPC1B, anticorps Arpc1b, anticorps EHI_094120, anticorps arpc1b, anticorps LOC100410640, anticorps arpc1b.S

Sujet:

Synonyms: Actin-related protein 2/3 complex subunit 1B, Arp2/3 complex 41 kDa subunit, p41-ARC, ARPC1B, ARC41

Background: Actin-related protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene. It is mapped to 7q22.1. This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

ID gène: 10095

UniProt: O15143

Pathways: Signalisation RTK, Regulation of Actin Filament Polymerization