NPBWR1 anticorps (AA 58-328)

N° du produit ABIN6719427

Détail du produit anti-NPBWR1 anticorps

Antigène: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Épitope: AA 58-328

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPBWR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Rabbit IgG polyclonal antibody for GPCR GPR7/NPBWR1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for GPCR GPR7/NPBWR1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GPCR GPR7/NPBWR1 recombinant protein (Position: V58-A328).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL Direct ELISA|0.1-0.5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur NPBWR1

Antigène: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Autre désignation: NPBWR1 (NPBWR1 Produits)

Synonymes: anticorps NPBWR1, anticorps GPR7, anticorps Gpr7, anticorps Nbpwr1, anticorps neuropeptides B/W receptor 1, anticorps neuropeptides B and W receptor 1, anticorps NPBWR1, anticorps Npbwr1

Sujet:

Synonyms: Neuropeptides B/W receptor type 1, G-protein coupled receptor 7, NPBWR1, GPR7

Background: Neuropeptides B/W receptor 1, also known as NPBW1 and GPR7, is a human protein encoded by the NPBWR1 gene. In rodent models, NPBWR1 is over-expressed in Schwann cells associated with neuropathic pain, suggesting it inhibits inflammatory pain responses. Mice without NPBW1 exhibited a stronger hostile reaction to intruders, suggesting NPBW1 has a role in stress responses.  Early studies indicated that NPB and NPW had a complex effect on appetite, but generally led to anorexia.[12] Similarly, male rats lacking NPBWR1 exhibited hyperphagiaand adult-onset obesity, though why female rats are unaffected is unknown. Researchers speculated that activating these pathways might decrease obesity, and synthesized a small-molecule ligand that is capable of stimulating both receptors at low concentrations.

ID gène: 2831

UniProt: P48145