COL17A1 anticorps

N° du produit ABIN6719519

Détail du produit anti-COL17A1 anticorps

Antigène: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL17A1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Collagen XVII/COL17A1 detection. Tested with WB in Human.

Séquence: KVFSAYSNVT ADLMDFFQTY GAIQ

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Collagen XVII/COL17A1 detection. Tested with WB in Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence of human Collagen XVII/COL17A1(KVFSAYSNVTADLMDFFQTYGAIQ).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur COL17A1

Antigène: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Autre désignation: COL17A1 (COL17A1 Produits)

Synonymes: anticorps col17a1, anticorps fk89a06, anticorps si:ch211-223p8.6, anticorps wu:fk89a06, anticorps COL17A1, anticorps BA16H23.2, anticorps BP180, anticorps BPA-2, anticorps BPAG2, anticorps LAD-1, anticorps Bpag, anticorps Bpag2, anticorps collagen type XVII alpha 1 chain, anticorps collagen, type XVII, alpha 1b, anticorps collagen, type XVII, alpha 1, anticorps Col17a1, anticorps col17a1b, anticorps COL17A1

Sujet:

Synonyms: Collagen alpha-1(XVII) chain, 180 kDa bullous pemphigoid antigen 2, Bullous pemphigoid antigen 2, 120 kDa linear IgA dermatosis antigen, Linear IgA disease antigen 1, LAD-1, 97 kDa linear IgA bullous dermatosis antigen, 97 kDa LAD antigen, 97-LAD, Linear IgA bullous disease antigen of 97 kDa, LABD97, COL17A1, BP180, BPAG2

Background: Collagen XVII, previously called BP180, is a transmembrane protein which plays a critical role in maintaining the linkage between the intracellular and the extracellular structural elements involved in epidermal adhesion. It is mapped to 10q25.1. This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.

ID gène: 1308