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PD-L1 anticorps (Biotin)

PD-L1 Reactivité: Humain FACS Hôte: Souris Monoclonal 29E-2A3 Biotin
N° du produit ABIN6727427
  • Antigène Voir toutes PD-L1 Anticorps
    PD-L1 (CD274 (PD-L1))
    Reactivité
    • 170
    • 108
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Humain
    Hôte
    • 126
    • 62
    • 17
    • 4
    • 4
    • 1
    Souris
    Clonalité
    • 108
    • 104
    • 2
    Monoclonal
    Conjugué
    • 98
    • 16
    • 13
    • 11
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Cet anticorp PD-L1 est conjugé à/à la Biotin
    Application
    • 138
    • 104
    • 60
    • 40
    • 37
    • 28
    • 17
    • 17
    • 16
    • 15
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Clone
    29E-2A3
    Isotype
    IgG2b, kappa
    Top Product
    Discover our top product PD-L1 Anticorps primaire
  • Indications d'application
    For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
    Commentaires

    Matching Isotype Control: Biotin Mouse Rat IgG2b, κ Isotype Control (ABIN7469803)

    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % Proclin300, 1 % BSA
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2~8°C. Do not freeze.
  • Antigène
    PD-L1 (CD274 (PD-L1))
    Autre désignation
    PD-L1 (PD-L1 Produits)
    Synonymes
    anticorps B7-H, anticorps B7H1, anticorps PD-L1, anticorps PDCD1L1, anticorps PDCD1LG1, anticorps PDL1, anticorps A530045L16Rik, anticorps B7h1, anticorps Pdcd1l1, anticorps Pdcd1lg1, anticorps Pdl1, anticorps RGD1566211, anticorps CD274 molecule, anticorps CD274 antigen, anticorps programmed cell death 1 ligand 2, anticorps CD274, anticorps Cd274, anticorps PDCD1LG2
    Sujet
    B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
    ID gène
    29126
    UniProt
    Q9NZQ7
    Pathways
    Cancer Immune Checkpoints
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