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SFRP1 anticorps (AA 201-314)

SFRP1 Reactivité: Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN674694
  • Antigène Voir toutes SFRP1 Anticorps
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Épitope
    • 14
    • 11
    • 8
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-314
    Reactivité
    • 61
    • 47
    • 39
    • 3
    • 2
    • 2
    • 1
    • 1
    Souris, Rat
    Hôte
    • 75
    • 9
    • 2
    • 2
    Lapin
    Clonalité
    • 77
    • 11
    Polyclonal
    Conjugué
    • 28
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SFRP1 est non-conjugé
    Application
    • 66
    • 32
    • 30
    • 12
    • 12
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human SFRP1
    Isotype
    IgG
    Top Product
    Discover our top product SFRP1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Wang, Xie, Xie, Wan, Ma, Qi, Yang: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." dans: Neuroreport, Vol. 26, Issue 12, pp. 695-702, (2015) (PubMed).

  • Antigène
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Autre désignation
    SFRP1 (SFRP1 Produits)
    Synonymes
    anticorps FRP, anticorps FRP-1, anticorps FRP1, anticorps FrzA, anticorps SARP2, anticorps 2210415K03Rik, anticorps AW011917, anticorps AW107218, anticorps AW742929, anticorps sFRP-1, anticorps CSFRP1, anticorps SFRP1, anticorps XfrzA, anticorps frp, anticorps frp-1, anticorps frp1, anticorps frzA, anticorps sarp2, anticorps sfrp1, anticorps LOC100231868, anticorps Srfp1a, anticorps wu:fd19b09, anticorps secreted frizzled related protein 1, anticorps secreted frizzled-related protein 1, anticorps Secreted frizzled-related protein 1, anticorps secreted frizzled-related protein 1a, anticorps secreted frizzled-related protein 1b, anticorps SFRP1, anticorps Sfrp1, anticorps sfrp1, anticorps sfrp1a, anticorps sfrp1b
    Sujet

    Synonyms: FRP, FRP1, FrzA, FRP-1, SARP2, Secreted frizzled-related protein 1, sFRP-1, Secreted apoptosis-related protein 2, SARP-2, SFRP1

    Background: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

    ID gène
    6422
    UniProt
    Q8N474
    Pathways
    Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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