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CD33 anticorps (AA 261-364)

CD33 Reactivité: Humain FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN676958
  • Antigène Voir toutes CD33 Anticorps
    CD33
    Épitope
    • 16
    • 15
    • 14
    • 13
    • 10
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 261-364
    Reactivité
    • 173
    • 35
    • 15
    • 13
    • 7
    • 6
    • 3
    • 1
    Humain
    Hôte
    • 99
    • 80
    Lapin
    Clonalité
    • 94
    • 84
    • 1
    Polyclonal
    Conjugué
    • 59
    • 17
    • 14
    • 13
    • 11
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD33 est non-conjugé
    Application
    • 107
    • 106
    • 44
    • 35
    • 25
    • 25
    • 23
    • 22
    • 15
    • 13
    • 10
    • 9
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CD33
    Isotype
    IgG
    Top Product
    Discover our top product CD33 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Shi, Jiang, Li, Shan, Li, An, Yang, Xu: "Sodium selenite alters microtubule assembly and induces apoptosis in vitro and in vivo." dans: Journal of hematology & oncology, Vol. 6, Issue 1, pp. 7, (2013) (PubMed).

    An, Shi, Wei, Hua, Ci, Jiang, Li, Wu, Hui, Yang, Xu: "The ROS/JNK/ATF2 pathway mediates selenite-induced leukemia NB4 cell cycle arrest and apoptosis in vitro and in vivo." dans: Cell death & disease, Vol. 4, pp. e973, (2013) (PubMed).

  • Antigène
    CD33
    Autre désignation
    CD33 (CD33 Produits)
    Synonymes
    anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps Siglec-3, anticorps gp67, anticorps CD33 molecule, anticorps CD33 antigen, anticorps CD33, anticorps Cd33
    Sujet

    Synonyms: p67, SIGLEC3, SIGLEC-3, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, gp67, CD33

    Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

    ID gène
    945
    UniProt
    P20138
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