TAF1 anticorps (AA 501-600) (Biotin)

N° du produit ABIN681075

Détail du produit anti-TAF1 anticorps (Biotin)

Antigène: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor (TAF1))

Épitope: AA 501-600

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAF1 est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TBP Associated Factor 1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur TAF1

Antigène: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor (TAF1))

Autre désignation: KAT4 (TAF1 Produits)

Sujet:

Synonyms: TBP Associated Factor 1, BA2R, CCG 1, CCG1, CCGS, Cell cycle G1 phase defect, Cell cycle gene 1 protein, Complementation of cell cycle block G1 to S, DYT3 protein, NSCL 2, NSCL2, OF, p250, TAF 1, TAF 2A, TAFII250, TAF1, TAF1 RNA polymerase II TATA box binding protein TBP associated factor 250 kDa, TAF1 RNA polymerase II TATA box binding protein TBP associated factor, TAF1 RNA polymerase II TATA box binding protein associated factor 250 kDa, TAF1_HUMAN, TAF2A, TAFII 250, TAFII-250, TAFII250, TAF II P250, TATA box binding protein TBP associated factor RNA polymerase II A, TATA box binding protein TBP associated factor RNA polymerase II A 250kD, TBP associated factor 250 kDa, TBP-associated factor 250 kDa, Transcription factor TFIID p250 polypeptide, Transcription initiation factor TFIID 250 kDa subunit, Transcription initiation factor TFIID subunit 1.

Background: Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle.

ID gène: 6872