RECK anticorps (AA 801-900)

N° du produit ABIN681418

Détail du produit anti-RECK anticorps

Antigène: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Épitope: AA 801-900

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RECK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RECK

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-RECK (ABIN681418)

Liu, Chi, Lu, Zhang, Yamakawa: "Reversion-inducing-cysteine-rich Protein with Kazal Motif Is Involved in Intimal Hyperplasia in Carotid Arteries: A New Insight in the Prevention of Restenosis after Vascular Angioplasty." dans: Annals of vascular surgery, Vol. 29, Issue 6, pp. 1293-9, (2015) (PubMed).

Siddesha, Valente, Sakamuri, Gardner, Delafontaine, Noda, Chandrasekar: "Acetylsalicylic acid inhibits IL-18-induced cardiac fibroblast migration through the induction of RECK." dans: Journal of cellular physiology, Vol. 229, Issue 7, pp. 845-55, (2014) (PubMed).

Détails sur RECK

Antigène: RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))

Autre désignation: RECK (RECK Produits)

Synonymes: anticorps ST15, anticorps St15, anticorps mRECK, anticorps reversion inducing cysteine rich protein with kazal motifs, anticorps reversion-inducing-cysteine-rich protein with kazal motifs, anticorps RECK, anticorps Reck

Sujet:

Synonyms: ST15, Reversion-inducing cysteine-rich protein with Kazal motifs, hRECK, Suppressor of tumorigenicity 15 protein, RECK

Background: Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

ID gène: 8434

UniProt: O95980