HLA-DRB3 anticorps

N° du produit ABIN6937422

Détail du produit anti-HLA-DRB3 anticorps

Antigène: HLA-DRB3 (Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-DRB3 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Specificité: This MAb reacts with the HLA-DRB3 antigen, a member of MHC class II molecules.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Réactivité croisée (Details): Human. Baboon. Chimpanzee. Monkey. Squirrel. Dog.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human REH cells (non-T, non-B leukemia cell line)

Clone: Bra30

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Ramos, Daudi or HuT78 cells. Tonsil or lymph node.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur HLA-DRB3

Antigène: HLA-DRB3 (Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3))

Autre désignation: HLA-DRB3 (HLA-DRB3 Produits)

Synonymes: anticorps HLA-DR3B, anticorps BLA-DRB3, anticorps Bota-DRB01, anticorps Bota-DRB02, anticorps Bota-DRB04, anticorps Bota-DRB07, anticorps Bota-DRB21, anticorps Bota-DRB22, anticorps LA-DRB, anticorps major histocompatibility complex, class II, DR beta 3, anticorps major histocompatibility complex, class II, DRB3, anticorps HLA-DRB3, anticorps BOLA-DRB3

Sujet: HLA class II histocompatibility antigen DR beta 3 chain, HLADR3B, Major histocompatibility complex, class II DR beta 3,HLA-DRB (MHC II)
Cellular localisation: Cell Surface

Poids moléculaire: ~28kDa (beta chain)

ID gène: 3123, 534322

UniProt: P01911

Pathways: TCR Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints