TCL1A anticorps (AA 2-109)

N° du produit ABIN6938517

Détail du produit anti-TCL1A anticorps

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Épitope: AA 2-109

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCL1A est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human TCL1 protein fragment (around aa 2-109) (exact sequence is proprietary)

Clone: TCL1-2078

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Ramos or Raji cells. Tonsil or T-cell Lymphoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur TCL1A

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Autre désignation: TCL1A (TCL1A Produits)

Synonymes: anticorps TCL1A, anticorps Tcl1a, anticorps TCL1, anticorps Tcl1, anticorps T-cell leukemia/lymphoma 1A, anticorps T cell lymphoma breakpoint 1, anticorps TCL1A, anticorps Tcl1, anticorps Tcl1a

Sujet: TCL1A, Lymphoma/leukemia, T-cell, Oncogene TCL1, P14 TCL1, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, T-cell leukemia/lymphoma 1A, TCL1, TCL1A,TCL1 (T-Cell Marker)
Cellular localisation: Nuclear and Cytoplasmic

Poids moléculaire: 14kDa

ID gène: 10232, 2484

UniProt: P56279

Pathways: Stem Cell Maintenance