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TLE1 anticorps (AA 175-338)

TLE1 Reactivité: Humain WB, IHC (f) Hôte: Souris Monoclonal TLE1-2085 unconjugated
N° du produit ABIN6938584
  • Antigène Voir toutes TLE1 Anticorps
    TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
    Épitope
    • 12
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 175-338
    Reactivité
    • 60
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 17
    • 1
    Souris
    Clonalité
    • 42
    • 19
    Monoclonal
    Conjugué
    • 39
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TLE1 est non-conjugé
    Application
    • 49
    • 25
    • 13
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein1 (TLE1) is a protein that isencoded by theTLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant fragment (aa 175-338) of human TLE1 (exact sequence is proprietary)
    Clone
    TLE1-2085
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product TLE1 Anticorps primaire
  • Indications d'application

    Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, HepG2 or Jurkat cells. Endometrium Carcinoma or Sarcomas.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
    Autre désignation
    TLE1 (TLE1 Produits)
    Synonymes
    anticorps ESG, anticorps ESG1, anticorps GRG1, anticorps C230057C06Rik, anticorps Estm14, anticorps Grg1, anticorps Tle4l, anticorps TLE1, anticorps transducin like enhancer of split 1, anticorps transducin-like enhancer protein 1, anticorps transducin-like enhancer of split 1, anticorps transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila), anticorps TLE1, anticorps Smp_150080, anticorps Tle1, anticorps LOC100354911, anticorps LOC100524475, anticorps LOC100061341
    Sujet
    Enhancer of split groucho 1 (ESG1), Enhancer of split groucho-like protein 1, GRG1, TLE1, Transducin like enhancer of split 1, Transducin-like enhancer protein 1,TLE1 (Synovial Sarcoma Marker)
    Cellular localisation: Nuclear
    Poids moléculaire
    83kDa
    ID gène
    7088, 197320, 689805
    UniProt
    Q04724
    Pathways
    Signalisation WNT, SARS-CoV-2 Protein Interactome
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