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Recombinant CD21 anticorps (AA 142-240)

CR2 Reactivité: Humain FACS, IHC, WB, IF, StM Hôte: Lapin Monoclonal CR2-3124R unconjugated Recombinant Antibody
N° du produit ABIN6939186
  • Antigène Voir toutes CD21 (CR2) Anticorps
    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
    Type d'anticorp
    Recombinant Antibody
    Épitope
    • 16
    • 16
    • 10
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 142-240
    Reactivité
    • 133
    • 28
    • 27
    • 16
    • 14
    • 11
    • 8
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 87
    • 69
    • 12
    Lapin
    Clonalité
    • 108
    • 59
    • 1
    Monoclonal
    Conjugué
    • 71
    • 22
    • 17
    • 16
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD21 est non-conjugé
    Application
    • 116
    • 65
    • 51
    • 40
    • 30
    • 28
    • 27
    • 16
    • 15
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Staining Methods (StM)
    Specificité
    Recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment (around aa 142-240) of human CR2 (CD21) protein (exact sequence is proprietary)
    Clone
    CR2-3124R
    Isotype
    IgG
    Top Product
    Discover our top product CR2 Anticorps primaire
  • Indications d'application

    Positive Control: MOLT4, WEHI-231 cells and Tonsil.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
    Autre désignation
    CR2 (CR2 Produits)
    Synonymes
    anticorps C3DR, anticorps CD21, anticorps CR, anticorps CVID7, anticorps SLEB9, anticorps Cd21, anticorps cd21, anticorps CR1, anticorps CR1-L, anticorps CR2, anticorps complement C3d receptor 2, anticorps complement C3b/C4b receptor 1 (Knops blood group), anticorps CR2, anticorps Cr2, anticorps CR1
    Poids moléculaire
    140kDa
    ID gène
    1380
    UniProt
    P20023
    Pathways
    Système du Complément
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