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CYP2E1 anticorps (C-Term)

CYP2E1 Reactivité: Humain IHC, StM Hôte: Souris Monoclonal M12P4H2 unconjugated
N° du produit ABIN6939224
  • Antigène Voir toutes CYP2E1 Anticorps
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    Épitope
    • 15
    • 10
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 70
    • 51
    • 37
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 78
    • 6
    • 3
    Souris
    Clonalité
    • 75
    • 12
    Monoclonal
    Conjugué
    • 44
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CYP2E1 est non-conjugé
    Application
    • 65
    • 26
    • 19
    • 14
    • 13
    • 9
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence)
    Clone
    M12P4H2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CYP2E1 Anticorps primaire
  • Indications d'application

    Positive Control: HepG2 cells. Liver.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    Autre désignation
    CYP2E1 (CYP2E1 Produits)
    Synonymes
    anticorps CYP2E1, anticorps CYP2E, anticorps CYPIIE1, anticorps CPE1, anticorps P450-J, anticorps P450C2E, anticorps Cyp2e, anticorps cytochrome P450, family 2, subfamily E, polypeptide 1, anticorps cytochrome P450 2E1, anticorps cytochrome P450 2E1-like, anticorps cytochrome P450 family 2 subfamily E member 1, anticorps cytochrome P450, family 2, subfamily e, polypeptide 1, anticorps CYP2E1, anticorps PTRG_07411, anticorps LOC100342572, anticorps LOC100727914, anticorps LOC101843716, anticorps Cyp2e1
    Sujet
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
    Poids moléculaire
    ~50-55kDa
    ID gène
    1571
    UniProt
    P05181
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