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KRT8 anticorps

KRT8 Reactivité: Humain WB, IF, IHC, FACS, StM Hôte: Souris Monoclonal TS1 unconjugated
N° du produit ABIN6939886
  • Antigène Voir toutes KRT8 Anticorps
    KRT8 (Keratin 8 (KRT8))
    Reactivité
    • 248
    • 81
    • 76
    • 32
    • 32
    • 30
    • 30
    • 16
    • 14
    • 10
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 132
    • 125
    • 2
    • 1
    Souris
    Clonalité
    • 129
    • 129
    Monoclonal
    Conjugué
    • 138
    • 23
    • 17
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Cet anticorp KRT8 est non-conjugé
    Application
    • 164
    • 97
    • 89
    • 83
    • 67
    • 50
    • 41
    • 40
    • 32
    • 29
    • 23
    • 18
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)
    Specificité
    Epitope of this MAb is located between aa343-357 (ELAIKDANAKLSELE). Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast.
    Aucune reactivité croisée
    Furet, Rat (Rattus)
    Purification
    Purified by Protein A/G
    Immunogène
    Keratin preparation from a human carcinoma
    Clone
    TS1
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product KRT8 Anticorps primaire
  • Indications d'application

    Positive Control: SK-OV-3, MCF-7, HeLa or A431 cells. Skin, colon, lung or breast carcinoma.

    Known Application: Western Blot (0.5-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    KRT8 (Keratin 8 (KRT8))
    Autre désignation
    KRT8 (KRT8 Produits)
    Synonymes
    anticorps CARD2, anticorps CK-8, anticorps CK8, anticorps CYK8, anticorps K2C8, anticorps K8, anticorps KO, anticorps AA960620, anticorps AL022697, anticorps AU019895, anticorps Card2, anticorps EndoA, anticorps Krt-2.8, anticorps Krt2-8, anticorps CYKER, anticorps KRT2-8, anticorps KERATIN8, anticorps ck8, anticorps cyk8, anticorps k2c8, anticorps card2, anticorps krt2-5, anticorps MGC69490, anticorps KRT8, anticorps DreK8, anticorps cb186, anticorps krt2-8, anticorps sb:cb186, anticorps wu:fa20h05, anticorps wu:fa95h10, anticorps wu:fb96c06, anticorps zf-K8, anticorps zfk8, anticorps DKFZp468F2127, anticorps keratin 8, anticorps keratin 8 S homeolog, anticorps KRT8, anticorps Krt8, anticorps krt8.S, anticorps krt8
    Poids moléculaire
    52.5kDa
    ID gène
    3856
    UniProt
    P05787
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