CD46 anticorps
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- Antigène Voir toutes CD46 Anticorps
- CD46
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Reactivité
- Humain, Babouin
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD46 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Specificité
- Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.
- Aucune reactivité croisée
- Cheval
- Immunogène
- Stimulated human leukocytes
- Clone
- 169-1-E4-3
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD46 Anticorps primaire
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- Indications d'application
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Positive Control: K562, U937, HL60, HeLa and Jurkat cells and human lymphocytes. Lymph node and tonsil.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- CD46
- Autre désignation
- CD46 (CD46 Produits)
- Synonymes
- anticorps AHUS2, anticorps MCP, anticorps MIC10, anticorps TLX, anticorps TRA2.10, anticorps Mcp, anticorps CD46, anticorps CD46 molecule, anticorps CD46 antigen, complement regulatory protein, anticorps CD46 molecule, complement regulatory protein, anticorps membrane cofactor protein-like, anticorps CD46, anticorps Cd46, anticorps LOC100341359, anticorps LOC103789310
- Poids moléculaire
- 52-58kDa
- ID gène
- 4179
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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