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MME anticorps (AA 583-740)

MME Reactivité: Humain IHC, ELISA, StM, Coat Hôte: Souris Monoclonal MME-2580 unconjugated
N° du produit ABIN6940063
  • Antigène Voir toutes MME Anticorps
    MME (Membrane Metallo-Endopeptidase (MME))
    Épitope
    • 16
    • 14
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 583-740
    Reactivité
    • 214
    • 58
    • 50
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 111
    • 109
    • 2
    Souris
    Clonalité
    • 116
    • 105
    • 2
    Monoclonal
    Conjugué
    • 109
    • 19
    • 19
    • 14
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MME est non-conjugé
    Application
    • 133
    • 101
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    • 38
    • 29
    • 22
    • 21
    • 13
    • 13
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Staining Methods (StM), Coating (Coat)
    Specificité
    Recognizes a 100 kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant human CD10 protein fragment (aa 583-740) (exact sequence is proprietary)
    Clone
    MME-2580
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product MME Anticorps primaire
  • Indications d'application

    Positive Control: Tonsil, small intestine or kidney (IHC).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    MME (Membrane Metallo-Endopeptidase (MME))
    Autre désignation
    MME (MME Produits)
    Synonymes
    anticorps CALLA, anticorps CD10, anticorps NEP, anticorps SFE, anticorps 6030454K05Rik, anticorps C85356, anticorps Nep, anticorps neprilysin, anticorps membrane metalloendopeptidase, anticorps membrane metallo endopeptidase, anticorps membrane metallo-endopeptidase, anticorps MME, anticorps Mme
    Classe de substances
    Chemical
    Poids moléculaire
    100kDa
    ID gène
    4311
    UniProt
    P08473
    Pathways
    Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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