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CD31 anticorps (AA 625-738)

PECAM1 Reactivité: Humain FACS, IHC, IF, StM Hôte: Souris Monoclonal PECAM1-3527 unconjugated
N° du produit ABIN6940277
  • Antigène Voir toutes CD31 (PECAM1) Anticorps
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Épitope
    • 18
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    AA 625-738
    Reactivité
    • 274
    • 142
    • 72
    • 59
    • 42
    • 28
    • 22
    • 18
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 158
    • 148
    • 48
    • 7
    • 3
    • 2
    Souris
    Clonalité
    • 232
    • 133
    • 1
    Monoclonal
    Conjugué
    • 156
    • 33
    • 33
    • 24
    • 11
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD31 est non-conjugé
    Application
    • 227
    • 186
    • 96
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    Specificité
    CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment (around aa 625-738) of human CD31 protein (exact sequence is proprietary)
    Clone
    PECAM1-3527
    Isotype
    IgG
    Top Product
    Discover our top product PECAM1 Anticorps primaire
  • Indications d'application

    Positive Control: Jurkat cells. Tonsil or Angiosarcoma.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Autre désignation
    PECAM1 (PECAM1 Produits)
    Synonymes
    anticorps CD31, anticorps CD31/EndoCAM, anticorps GPIIA', anticorps PECA1, anticorps PECAM-1, anticorps endoCAM, anticorps C85791, anticorps Cd31, anticorps Pecam, anticorps platelet/endothelial cell adhesion molecule 1, anticorps platelet and endothelial cell adhesion molecule 1, anticorps pecam1, anticorps PECAM1, anticorps Pecam1
    Poids moléculaire
    ~100kDa (endothelium) and ~130kDa (platelets)
    ID gène
    5175
    UniProt
    P16284
    Pathways
    Regulation of Actin Filament Polymerization
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