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Oct-2 anticorps (AA 112-297)

POU2F2 Reactivité: Humain IHC, StM Hôte: Souris Monoclonal Oct2-2136 unconjugated
N° du produit ABIN6940358
  • Antigène Voir toutes Oct-2 (POU2F2) Anticorps
    Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
    Épitope
    • 15
    • 12
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 112-297
    Reactivité
    • 74
    • 41
    • 21
    • 18
    • 16
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 65
    • 8
    • 1
    • 1
    Souris
    Clonalité
    • 64
    • 11
    Monoclonal
    Conjugué
    • 35
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp Oct-2 est non-conjugé
    Application
    • 66
    • 31
    • 24
    • 24
    • 13
    • 9
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)
    Clone
    Oct2-2136
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product POU2F2 Anticorps primaire
  • Indications d'application

    Positive Control: Raji or U-937 cells. Spleen or Tonsil.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
    Autre désignation
    POU2F2 (POU2F2 Produits)
    Synonymes
    anticorps OCT2, anticorps OTF2, anticorps Oct-2, anticorps Pou2f2, anticorps Oct2a, anticorps Oct2b, anticorps Otf-2, anticorps Otf2, anticorps 2-Oct, anticorps Oct2, anticorps POU class 2 homeobox 2, anticorps POU domain, class 2, transcription factor 2, anticorps solute carrier family 22 (organic cation transporter), member 2, anticorps POU2F2, anticorps Pou2f2, anticorps SLC22A2
    Sujet
    Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of Oct-2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
    Poids moléculaire
    60kDa
    ID gène
    5452
    UniProt
    P09086
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