Oct-2 anticorps (AA 112-297)
-
- Antigène Voir toutes Oct-2 (POU2F2) Anticorps
- Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
-
Épitope
- AA 112-297
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp Oct-2 est non-conjugé
-
Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)
- Clone
- Oct2-2136
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product POU2F2 Anticorps primaire
-
-
- Indications d'application
-
Positive Control: Raji or U-937 cells. Spleen or Tonsil.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
-
- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
-
- Antigène
- Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
- Autre désignation
- POU2F2 (POU2F2 Produits)
- Synonymes
- anticorps OCT2, anticorps OTF2, anticorps Oct-2, anticorps Pou2f2, anticorps Oct2a, anticorps Oct2b, anticorps Otf-2, anticorps Otf2, anticorps 2-Oct, anticorps Oct2, anticorps POU class 2 homeobox 2, anticorps POU domain, class 2, transcription factor 2, anticorps solute carrier family 22 (organic cation transporter), member 2, anticorps POU2F2, anticorps Pou2f2, anticorps SLC22A2
- Sujet
- Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of Oct-2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
- Poids moléculaire
- 60kDa
- ID gène
- 5452
- UniProt
- P09086
-