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Recombinant CD45 anticorps

PTPRC Reactivité: Humain FACS, IHC, WB, IF, StM Hôte: Souris Monoclonal rPTPRC-1460 unconjugated Recombinant Antibody
N° du produit ABIN6940452
  • Antigène Voir toutes CD45 (PTPRC) Anticorps
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 418
    • 252
    • 88
    • 29
    • 20
    • 16
    • 15
    • 10
    • 7
    • 6
    • 6
    • 6
    • 4
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 304
    • 201
    • 148
    • 2
    • 1
    • 1
    Souris
    Clonalité
    • 512
    • 137
    • 1
    Monoclonal
    Conjugué
    • 184
    • 62
    • 54
    • 52
    • 39
    • 17
    • 15
    • 12
    • 12
    • 12
    • 10
    • 10
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp CD45 est non-conjugé
    Application
    • 533
    • 212
    • 159
    • 137
    • 134
    • 80
    • 70
    • 60
    • 47
    • 27
    • 19
    • 17
    • 14
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    • 3
    • 3
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    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Human recombinant full-length CD45 protein
    Clone
    RPTPRC-1460
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product PTPRC Anticorps primaire
  • Indications d'application

    Positive Control: Ramos, U-698 or GA-10 cells. Tonsil and Spleen.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    Autre désignation
    PTPRC (PTPRC Produits)
    Synonymes
    anticorps PTPRC, anticorps si:dkeyp-47c5.1, anticorps B220, anticorps CD45, anticorps CD45R, anticorps GP180, anticorps L-CA, anticorps LCA, anticorps LY5, anticorps T200, anticorps Cd45, anticorps Ly-5, anticorps Lyt-4, anticorps loc, anticorps Lca, anticorps RT7, anticorps cd45, anticorps protein tyrosine phosphatase, receptor type C, anticorps protein tyrosine phosphatase, receptor type, C, anticorps receptor-type tyrosine-protein phosphatase C, anticorps PTPRC, anticorps ptprc, anticorps LOC100074271, anticorps Ptprc
    Sujet
    CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
    Poids moléculaire
    180-220kDa
    ID gène
    5788
    UniProt
    P08575
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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