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Recombinant S100A8 anticorps

S100A8 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Chien, Singe, Cat, Cheval, Cobaye, Babouin, Chévre IHC, StM Hôte: Lapin Monoclonal MAC3157R unconjugated Recombinant Antibody
N° du produit ABIN6940549
  • Antigène Voir toutes S100A8 Anticorps
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Chien, Singe, Cat, Cheval, Cobaye, Babouin, Chévre
    Hôte
    • 80
    • 38
    • 3
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 86
    • 40
    Monoclonal
    Conjugué
    • 64
    • 21
    • 16
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp S100A8 est non-conjugé
    Application
    • 75
    • 46
    • 43
    • 31
    • 16
    • 15
    • 15
    • 14
    • 13
    • 12
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificité
    Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12 kDa alpha chain and a 14 kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer's cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
    Purification
    Purified by Protein A/G
    Immunogène
    Affinity Purified monocyte membrane preparation
    Clone
    MAC3157R
    Isotype
    IgG
    Top Product
    Discover our top product S100A8 Anticorps primaire
  • Indications d'application

    Positive Control: Tonsil, lymph node or spleen.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    Autre désignation
    S100A8 & S100A9 (S100A8 Produits)
    Synonymes
    anticorps 60B8AG, anticorps CAGA, anticorps CFAG, anticorps CGLA, anticorps CP-10, anticorps L1Ag, anticorps MA387, anticorps MIF, anticorps MRP8, anticorps NIF, anticorps P8, anticorps Mrp8, anticorps S100A8, anticorps 60B8Ag, anticorps AI323541, anticorps B8Ag, anticorps CFAg, anticorps Caga, anticorps p8, anticorps MRP-8, anticorps S100 calcium binding protein A8, anticorps S100 calcium binding protein A8 (calgranulin A), anticorps S100A8, anticorps S100a8
    Poids moléculaire
    12-14kDa (doublet)
    ID gène
    6279, 6280
    UniProt
    P05109, P06702
    Pathways
    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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