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Recombinant Thyroglobulin anticorps

TG Reactivité: Humain IHC, StM Hôte: Lapin Monoclonal TGB-1968R unconjugated Recombinant Antibody
N° du produit ABIN6940714
  • Antigène Voir toutes Thyroglobulin (TG) Anticorps
    Thyroglobulin (TG)
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 104
    • 36
    • 36
    • 2
    • 1
    Humain
    Hôte
    • 58
    • 43
    • 5
    • 4
    • 1
    • 1
    Lapin
    Clonalité
    • 65
    • 44
    Monoclonal
    Conjugué
    • 69
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Thyroglobulin est non-conjugé
    Application
    • 39
    • 38
    • 31
    • 27
    • 18
    • 16
    • 12
    • 11
    • 10
    • 9
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant full-length human Thyroglobulin protein
    Clone
    TGB-1968R
    Isotype
    IgG
    Top Product
    Discover our top product TG Anticorps primaire
  • Indications d'application

    Positive Control: Thyroid.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    Thyroglobulin (TG)
    Autre désignation
    Thyroglobulin (Thyroidal Cell Marker) (TG Produits)
    Synonymes
    anticorps TG, anticorps cb717, anticorps AITD3, anticorps TGN, anticorps Tgn, anticorps cog, anticorps thyroglobulin, anticorps TG, anticorps tg, anticorps LOC701526, anticorps LOC701756, anticorps LOC100434297, anticorps Tg
    Sujet
    Thyroglobulin is a 660 kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
    Poids moléculaire
    660kDa (Dimeric Form)
    ID gène
    7038
    UniProt
    P01266
    Pathways
    Thyroid Hormone Synthesis
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